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Afatinib superior to Erlotinin in Lung Cancer

Recently details of the LUXLung 8 phase 3 trial became available. This study compared afatinib with erlotinib as second-line treatment for squamous cell carcinoma of the lung.

Afatinib was better with respect to all parameters – median progression-free survival, overall survival and patient-reported quality of life outcome (using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 LC13).

Rates of improved global health status/quality of life (35.7% vs 28.3%; P = .041) and cough (43.4% vs 35.2%; P = .029) were significantly greater with afatinib than erlotinib.?
Afatinib significantly delayed time to deterioration of dyspnea versus erlotinib (2.6 vs 1.9 months; P = .008), with a trend toward delayed time to deterioration of cough with afatinib.

Changes in mean scores over time favored afatinib over erlotinib significantly for cough (P = .0091), dyspnea (P = .0024), and pain (P = .0384).

This is how we improve quality of life and survival for patients with lung cance

Why Parent Feel the Loss of a Child So Deeply

An undisputed leader in the field, the Ophthalmology Department boasts of successfully treating over 30, 000 patients every year. Trust our board certified and fellow trained ophthalmologists to offer you a complete range of comprehensive, sub-specialty, surgical as well as non-invasive treatments for any of the eye area like the retina, vitreous humor, cornea, glaucoma, strabismus corrections and oculoplastics.

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Brain-Stimulating Activities May Keep You Sharp

The clinic stands apart in going a step ahead and working with the patient’s health care team to come up with a comprehensive treatment plan. This is because of the insight that many eye conditions stem from other medical conditions like diabetes, thyroid disorder, immune systems, etc. Resources are also offered to complement the local physician’s expertise.

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